Frequently asked questions

GlutenDetect is now available and you can order it in pharmacies and online in www.sensafarma.es, the digital platform of Bidafarma, Biomedal´s distribution partner in Spain.

At www.glutendetect.es you can also find 6- or 12-month subscriptions that will allow you to see how well you control your diet over time.

It is similar to a pregnancy test with minimal additional manipulations. Gluten fragments known as Gluten Immunogenic Peptides (GIP) in the sample react with an antibody (G12) on the strip. If a single green line appears, it means that no gluten was detected in the sample, but if two lines appear –one green and one red- gluten has been detected, indicating a gluten intake within the preceding hours (urine) or days (stools). The result can be read between 15-30 minutes.

Gluten Immunogenic Peptides (GIP) are fragments of gluten proteins that are resistant to gastrointestinal digestion, and which trigger immunologic reactions in subjects sensitive to gluten such as coeliac patients and patients with gluten sensitivity. These peptides are detectable in feces and urine.

No, they can be found in anyone who ingests gluten. However, they only trigger immune response in coeliacs.

Gluten is excreted into urine quickly, whereas it persists in the intestine for days. Urine therefore is most appropriate for determining acute contamination over the previous 20 hours whereas stool is most appropriate for monitoring compliance over a longer period of time (previous 2-7 days).

Establishing the exact amount of gluten that results in a positive indicator is complicated, since it depends on the metabolism of each person. However, it has been shown that the test can detect intakes of 50 mg gluten/day, which is the smallest amount of gluten that is harmful to coeliac patients. The average gluten intake of a person not subject to the gluten-free diet is 10-30 grams/day.

Establishing the exact amount of consumed gluten that results in a positive result is complicated, since it depends on the metabolism of each person. However, it has been shown that the test can detect intakes of 50 mg gluten/day, which is the smallest amount of gluten that is harmful to coeliac patients. The average gluten intake of a person not subject to the gluten-free diet is 10-30 grams/day.

It is 0.15 microgram (µg) of GIP per gram (g) of feces and 2.2 nanograms (ng) of GIP per millilitre (mL) of urine.

This is one of the most common errors we come across. Recent clinical studies show that more than 70% of coeliac patients who do not have symptoms present atrophy (damage) of the intestinal mucosa. Although many patients’ base compliance with their diet on the absence of symptoms, they may still have been ingesting gluten without knowing it. These small intakes are only detectable through gluten fragments excreted in faeces and urine.

It is important to be clear that a minimum amount of gluten causes damage to the coeliac’s body, regardless of whether or not it results in symptoms. Intestinal damage always occurs. GlutenDetect checks for this silent consumption of gluten and helps you locate where it may be coming from.

No. Most of coeliacs that eat gluten don´t feel symptoms. However, some studies have found gluten fragments on these patients’ feces, which is a trustworthy sign on gluten intake.

According to recent clinical trials, almost 80% of GIP-positive patients ( traces of gluten in feces) who say they follow a gluten-free diet do not suffer from symptoms. Another study shows that almost all coeliacs who eat less than half a gram of gluten, equivalent to a canapé, have no symptoms. In conclusion, it is not advisable to base compliance with the diet on the absence of apparent symptoms, because although small intakes of gluten go unnoticed, they silently influence the long-term consequences.

The damage caused by small, continuous intakes of gluten is cumulative and in the long term prevents the recovery of the intestinal mucosa. This damage causes villi to lose their ability to absorb nutrients and increases the probability of future more serious diseases such as lymphomas, autoimmune diseases and bone weakness.

According to recent clinical studies, when three urine samples are measured throughout the week and the result is negative, there is more than a 97% chance that the intestine is in good condition.
Similarly, two negative stool tests over a week would indicate good compliance with the gluten-free diet.
Our recommendation would be to measure 3 urine samples, preferably one of them on the weekend, taking the first urine in the morning, or 2 stool samples over a week with 3-4 days between them.
The tests should be used on a regular basis (weekly, every two weeks, monthly…) to monitor compliance with the gluten-free diet over time.

The test is qualitative. A red line, regardless of its intensity, indicates the presence of gluten and a positive result.

According to different studies, gluten intake, whether voluntary or involuntary, is common among celiac patients. It is estimated that almost 90% of celiacs could intake gluten at least once a month. However, the absence of gluten peptides in many tests (more than 80% negative), could allow the intestine to heal, avoiding villous atrophy. Following a gluten-free diet day after day is difficult, but, in any case, it is important to assess the degree of exposure to gluten in daily habits or changing environmental circumstances (for example, after meals away from home).